(A) The binding site of miR-433-3p on GATA3 3′-UTR region. (B) Dual luciferase reporter assay was used to validate the binding relationship between miR-433-3p and GATA3 in THP-1-differentiated macrophages. (C) qRT-PCR was performed to assess the expression of miR-433-3p in THP-1-differentiated macrophages transfected with miR-433-3p mimics or miR-433-3p inhibitor. (D) qRT-PCR was performed to assess the expression of GATA3 in THP-1-differentiated macrophages transfected with miR-433-3p mimics or miR-433-3p inhibitor. Data with error bars are presented as the mean ± SD; The Student’s t test and one-way ANOVA test were used to determine significance; *P<0.05, **P<0.01, ***P<0.001.