Figure 2.
Cartoon illustrating the main domain features of human factors impacting decapping and translation initiation discussed in this review, and their interactions.
Definitions not in text: DCP1A TD trimerization domain; DCP2 NRD — N-terminal conserved a-helical regulatory domain, Nudix its catalytic domain, FEB phenylalanine-rich EDC4-binding motif; EDC3 Lsm — Like Sm domain, FDF motif contains the indicated amino acids. Approximate positions of amino acid changes and insertions are indicated with blue bars and triangles. Not to scale.