(A) The protein expression levels of E-cadherin, N-cadherin, vimentin, and occludin. (B,C) The protein expression levels of E-cadherin and N-cadherin. (D,E) The intensity/per cell of E-cadherin and N-cadherin, respectively. Groups: HG, HG-induced NRK-52E cells; HG + NC, HG-induced NRK-52E cells with NC; HG + AS-IV, HG-induced NRK-52E cells treated with 80 μg/ml AS-IV; HG + AS-IV + SRI-011381, HG-induced NRK-52E cells treated with 80 μg/ml AS-IV, and the TGF-β1 activator SRI-011381. NRK-52E cells without any treatment served as the control group. All data are presented as mean ± SD. *P<0.05, **P<0.01, ***P<0.001 compared with the control group. ^##P<0.01 compared with the HG group. ^$P<0.05 compared with the HG + AS-IV group.