(A) Representative results of SIRT1 immunohistochemistry in myocardial tissues. (B) SIRT1 expression in nuclei in myocardial tissue detected by Western blot analysis. (C,D) mTOR (C) LC3II/LC3I, p62 and Beclin-1 (D) expression in myocardial tissues measured by Western blot analysis. The data are expressed as the mean ± standard deviation, n=6. The t test was employed to analyze comparisons between two groups. *P<0.05, compared with the MI/R + Dex group.