(A) qRT-PCR detection of miR-101-3p and PTGS2 expression in synovial tissue of patients with RA. (B) Western blot analysis detection of PTGS2 protein expression in synovial tissue of patients with RA. (C) Expression levels of miR-101-3p and PTGS2 in synovial tissue of RA rats. (D) Western blot analysis detection of PTGS2 protein expression in synovial tissue of RA rats. (E) Expression levels of miR-101-3p and PTGS2 in synovial tissue of RA rats with interference of miR-101-3p and PTGS2 expression. (F) PTGS2 protein expression in synovial tissue of RA rats with interference of miR-101-3p and PTGS2 expression. The data analysis between the two groups was compared with the t test. The data analysis among multiple groups was performed using one-way ANOVA, followed by pairwise comparison using LSD-t. *P<0.05 vs. the normal tissues. ^aP<0.05 vs. the normal group; ^bP<0.05 vs. the mimic-NC group; ^cP<0.05 vs. the sh-NC group; ^dP<0.05 vs. the miR-101-3p inhibitors + sh-NC group.