Notes: AMC-HN-8 and M4E cells transfected with si-NC, si-XIST, si-XIST+anti-miR-NC or si-XIST+anti-miR-125b-5p were classified as four groups, respectively. (A and B) QRT-PCR was used to quantify miR-125b-5p expression in the above four groups. (C and D) Cell proliferation was examined by CCK-8 assay. (E and F) By flow cytometry assay, the apoptosis rate of cells was detected in four groups. (G and H) Analysis of cell migration and invasion in four groups was conducted by Transwell assay; *P <0.05