Figure 8
(A) Activation of astrocytes (GFAP) was measured by immunohistochemical staining. Hippocampus (Hp) scale bar, 200 μm; CA3 and DG scale bar, 100 μm. (B) Average optical density (AOD) was used to analyze the activation of astrocytes. Data were present as mean ± SD (n = 3 each group, two-way ANOVA). **, P < 0.01 versus Vector-PBS.
LPS does not enhance P301L-mediated astrocytes activation in DG subset, and addition of GC did not attenuate astrocyte activation

(A) Activation of astrocytes (GFAP) was measured by immunohistochemical staining. Hippocampus (Hp) scale bar, 200 μm; CA3 and DG scale bar, 100 μm. (B) Average optical density (AOD) was used to analyze the activation of astrocytes. Data were present as mean ± SD (n = 3 each group, two-way ANOVA). **, P < 0.01 versus Vector-PBS.

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