Figure 2
![Sequence alignment of BpeGReg and PccGCS. (A) Conserved distal tyrosine (hydrogen bonds with oxygen). (B) Conserved distal serine (helps stabilize bound oxygen). (C) Conserved tryptophan (in contact with edge of heme). (D) Conserved proximal histidine (holds heme in globin domain). (E) Conserved π-helical region. (F) Product-binding inhibitory site (I-site) motif (RxxD). (G) Active site motif (GGEEF). Alignment and image created using MultAlin [40] and ESPript 3.0 [41].](https://port.silverchair-cdn.com/port/content_public/journal/bioscirep/40/2/10.1042_bsr20193602/1/bsr-2019-3602i002.png?Expires=1716990929&Signature=WkzN0LZWANnX3uKB9usq8aF0zkoHbcbEAFu62LCeB69eJYGwtHs-QU~0iS2xACO0SFPXzKoMRIddBckuw-KnP-R8OnfdRySqvrbsuAtIljLSjPfPQ2gsOmWdRnI7aFvGljvsRFLEU8DEgYLOGPG3OIQ5T0ulE0vsUEGnwOtwepDnuTaGhc4DiaTGan5XYi1JWqgfRVK0A90TQo4Vfbtgu2S9eCf-H~8PXwBKk-HeZat1omUKTEGRlojdPH3cKWrg309sOwlyWY12NNUQr~el2HI0nyyHcVaApO~EJH8Rb2HcsnkBoAG5XdfhsYhTlnmjTi8Peb9Gy3ySq8p42QIXiQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Sequence alignments
Sequence alignment of BpeGReg and PccGCS. (A) Conserved distal tyrosine (hydrogen bonds with oxygen). (B) Conserved distal serine (helps stabilize bound oxygen). (C) Conserved tryptophan (in contact with edge of heme). (D) Conserved proximal histidine (holds heme in globin domain). (E) Conserved π-helical region. (F) Product-binding inhibitory site (I-site) motif (RxxD). (G) Active site motif (GGEEF). Alignment and image created using MultAlin [40] and ESPript 3.0 [41].