Changes in faecal microbial diversities between the PE group (n=27) and the HPC group (n=36)
(A) Rarefaction curves for the OTU levels. (B) The number of OTU present in the HPC only (blue), PE patients only (red), or overlap between the two groups in a Venn diagram. (C) PCoA was performed by using Bray–Curtis analysis method to calculate the distance between the PE and HPC groups in faecal samples. The percentages shown on each axis explain the proportion of each dimension. (D) Faecal biomasses were measured between both groups. NS, not significant. (E,F) Comparison of the microbial α diversity using the Shannon index and Sobs index, based on the OTU levels in both groups. Wilcoxon’s test was performed. ***P<0.001.