(A) FMN2 expression in CRC and normal samples from the TCGA COAD dataset. (B) Kaplan–Meier analyses of the correlations between FMN2 expression and OS of COAD patients from the TCGA COAD dataset. (C) Kaplan–Meier analyses of the correlations between FMN2 expression and DFS of COAD patients from the TCGA COAD dataset. (D) IHC assay indicated the expression of FMN2 was significantly down-regulated in CRC tissues compared with adjacent non-tumorous tissues. (E) The qRT-PCR assay indicated circFMN2 knockdown did not change the mRNA level of FMN2. (F) The Western blot assay indicated circFMN2 knockdown did not change the protein level of FMN2. *P<0.05.