Effect of adrenergic receptor blockers, propranol and prazosin, on blood pressure and natriuresis
Effect of adrenergic receptor blockers, propranolol and prazosin, on SBP (A), DBP (B), urine volume (C), and urine sodium (D) in adult rat prenatal cold-exposed and control offspring. Propranolol (non-selective β antagonist, 30 mg/kg) and prazosin (specific α1 adrenergic receptor antagonist, 1 mg/kg) were administered into the stomach with a gastric tube twice daily for 1 week from 11 to 12 weeks of age. SBP and DBP were recorded by the tail-cuff method in conscious prenatal cold-exposed and control offspring. (*P<0.05 vs control, #P<0.05 vs others, n=5/group).