Predictive function analysis and discriminate predictive model for the gut microbiota

Significant KEGG pathways are shown for the fecal microbiome (A), statistical analysis was performed with the Kruskal–Wallis test. *P<0.05, **P<0.01, ***P<0.001, compared with the control group or OSAHS groups. OSAHS patients could be separated from controls using 29 genera, with an ROC-AUC of 0.789 (B). FPR: false positive rate; TPR: true positive rate. Control: patients with AHI ≤ 5 events/h were considered as non-OSAHS; Group 1: patients with 5 < AHI ≤ 15 were considered as mild OSAHS; Group 2: patients with 15 < AHI ≤ 30 were considered as moderate OSAHS; Group 3: patients with AHI ≥ 30 were considered as severe OSAHS.