Figure 4
(A) CCK-8 assay was performed to detect the cell viability after transfecting with miR-365 and treating with LY294002. (B–D) Influences of miR-365 overexpression and LY294002 treatment on the Akt, mTOR, S6K mRNA expression. (E) Influences of miR-365 overexpression and LY294002 treatment on the p-Akt, p-mTOR, p-S6K protein expression. Each point represents the relative mean ± SD. * denotes significance (P<0.05).
Influences of miR-365 and LY294002 treatment on PI3K/Akt/mTOR/S6K signaling pathway related genes

(A) CCK-8 assay was performed to detect the cell viability after transfecting with miR-365 and treating with LY294002. (B–D) Influences of miR-365 overexpression and LY294002 treatment on the Akt, mTOR, S6K mRNA expression. (E) Influences of miR-365 overexpression and LY294002 treatment on the p-Akt, p-mTOR, p-S6K protein expression. Each point represents the relative mean ± SD. * denotes significance (P<0.05).

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