The images show projection views of fluorescence recorded in a single migrating primary human keratinocyte (A) and collectively migrating primary human epidermal keratinocytes (B) detecting the distribution of paxillin-labeled FAs and β4-integrin-labeled HDLAs. The direction of migration is shown by arrows and the nuclei are demarcated in blue by DAPI staining. Note the presence of highly ordered arrays consisting of chevron-like hemidesmosomal adhesions with intercalated FAs in the single migrating keratinocyte in A and the leader cell (number 1) of the collectively migrating cell sheet (nuclei of followers numbered 2–6). The broken line shows the position of the barrier that was lifted to allow collective cell migration (B was adapted from Pora et al. [79]).