(A) In three pancreatic cancer PDX models, FOXM1 expression levels were analyzed by IHC. Scale bar, 100 μm. (B) These PDX tumor sizes were shown after grouping and treatment for 3 weeks. (C) The inhibition rate of gemcitabine treatment for each PDX model. (D) The expression of FOXM1, p-P65, and apoptotic proteins Bcl2 and Bax in the tumor tissues after treatment was detected by Western blotting. *P<0.05; **P<0.01; ***P<0.001.