MiR-543 inhibited the PTEN/PI3K/AKT pathway and activated apoptosis-related proteins
(A) Protein expression levels of PTEN, p-AKT, AKT, Bcl-2, BAX, P21, and P53 were assayed by Western blotting in HCT8 cells. (B) Statistical analysis. *P<0.05 vs control; **P<0.01 vs control. The data are presented as the mean ± S.D. of triplicate experiments.