MiR-543 is up-regulated in HCT8/FU cells compared with its isogenic parental cells HCT8
(A) Dose–response curves of HCT8 and HCT8/FU cell lines towards 5-FU. The IC50 values are listed in the tables below. (B) The qRT-PCR analysis of miR-543 expression in HCT8 and HCT8/FU cell lines. **P<0.01 vs HCT8; data represent the mean ± S.D.; n=3. (C) HCT8 and HCT8/FU cell migration ability were evaluated by a Transwell assay. Representative fields of invading cells on the membrane were observed by an inverted microscope (magnification, ×20) **P<0.01 vs HCT8 cells.