MiR-495 inhibits the number of inflammatory leukocytes in the FV tissues and the ratio of weight to length of thrombus by inhibiting IL1R1/TLR4 signaling pathway
(A) HE staining was used to detect the pathological changes of FV thrombosis in mice; (B) a statistical map of the ratio of weight to length of thrombus in each group; (C) the statistical map of the number of leukocytes in each group of thrombus; (D) miR-495 expression in the plasma of each group was detected by RT-qPCR; (E,F) protein expressions of IL1R1 and TLR4 signaling-related genes in venous thrombosis tissues by Western blot analysis; *, P<0.05 compared with the normal group; #, P<0.05 compared with the blank, NC, and siRNA-NC groups.