SIRT1 was down-regulated in the synovial tissues and FLS of RA patients
SIRT1 mRNA expression relative to GAPDH was measured by RT-qPCR in synovial tissues (A) and FLS (B) from healthy negative control subjects (NC, N = 6) and rheumatoid arthritis patients (RA, N = 12). Mean ± SD; **P < 0.01.