(A) NM (5 μM) was incubated with agitation for 4 h at 25°C plus or minus the indicated foldamer (20 μM). NM fibrillization was assessed by ThT fluorescence. Values represent means±S.E.M. (n=3). A one-way ANOVA with the post-hoc Dunnett's multiple comparisons test was used to compare NM alone to each NM plus foldamer condition (* denotes P< 0.05). (B) GST-FUS (5 μM) was incubated in the presence of the indicated foldamer (20 μM) plus TEV protease at 25°C for 0–90 min. Turbidity measurements (absorbance at 395 nm) were taken every minute to assess aggregation. A representative dataset is shown.