Location of the hydrophilic loop of Nqo7 subunit (T. thermophilus [1]), shown in blue, which is homologous with mitochondrially encoded subunit ND3
(A) The Ser36 homologue of Cys39 of ND3 is shown in purple and proline residues are shown in cyan. Note that this loop is located in close proximity to the quinone-binding site and terminal cluster N2. (B) Partial alignment of the homologues of ND3. Hydrophilic loop containing the critical Cys39 is shown in a box.