(A) Total levels of proteinogenic amino acids (µmol/l ± S.E.M.) were measured in culture medium conditioned by healthy (n=3) or preeclamptic (n=3) placental explants, following pre-treatment with no NPs, blank-NPs or MitoQ-NPs. (B) Log 2 fold change values are shown for those microRNAs that were significantly altered in PE medium (n=4) compared with healthy medium (n=4) (blue). Log fold changes of those same microRNAs in medium conditioned by preeclamptic placental explants treated with MitoQ-NPs (n=3), compared with untreated PE medium, are shown in orange.