Figure 4.
Model of the Bro1 and coiled-coil domains of HD-PTP based on crystal and solution structures, and extended to include the proximal region of the PRR. Bound UBAP1 and CHMP4B peptides are shown based on crystal structures.
HD-PTP acts as an open ESCRT-binding scaffold.

Model of the Bro1 and coiled-coil domains of HD-PTP based on crystal and solution structures, and extended to include the proximal region of the PRR. Bound UBAP1 and CHMP4B peptides are shown based on crystal structures.

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