(A) Representative images of heart sections subjected to H&E, WGA, TRI, and PSR staining (200× magnification) from the left ventricles of wild-type (WT + I3C) and prorenin transgenic (TG) rats fed with 0.3% I3C (TG + I3C). (B) The statistical results of cardiomyocyte cross-sectional areas, LV collagen volume and perivascular collagen volume in each group (n=5/each group). *P<0.05 compared with WT + I3C rats.