Representative photomicrographs of glomeruli stained with PAS staining (A) and glomerular immunofluorescent staining for FN (B) and Col I (C) from male and female wild-type (WT) and transgenic (TG) rats fed with I3C or without I3C. Magnification 400×. Graphic quantitative evaluations of glomerular matrix score, FN staining score, and Col I staining score are shown on the right. *P<0.05 compared with male WT rats fed without I3C. ^#P<0.05 compared with female WT rats fed without I3C. n=5/each group.