Prognostic analyses using serum LTBP2 concentrations
(A,B) Time-dependent ROC curves for all-cause death and death by respiratory events, respectively. Integrated AUC (iAUC) was calculated for each cut-off value of serum LTBP2 concentration. The cut-off value with the highest iAUC was estimated commonly as 18 ng/ml. (C,D) Survival curves drawn by the Kaplan–Meyer method using the cut-off value of 18 ng/ml for all-cause death and death by respiratory events, respectively. The prognostic difference was statistically significant (P<0.001 by log-rank test in both situations).