Figure 3
In this figure, datasets on human samples from one cohort (CYREBAC cohort) are presented. The AM were enriched from BAL cell samples harvested from healthy volunteers and stimulated with WTC. The concentrations of IL-26 in the cell-free conditioned media were measured using ELISA. Gene expression analyses on the cells were performed using RT-PCR. (A) IL-26 protein concentrations in cell-free conditioned media from AM (n=4). The rest of the graphs show gene expression for (B) IL-26, (C) IL-10R2, (D) IL-20R1, (E) NF-κB, (F) STAT1, and (G) STAT3 in AM. The P-values are according to the parametric paired t test whereby (A,B) are according to the one-tailed test and (C–G) according to the two-tailed test. The horizontal lines indicate means and the P-values <0.05 are considered significant.
IL-26 production in AM and gene expression of functionally related genes in response to WTC in vitro

In this figure, datasets on human samples from one cohort (CYREBAC cohort) are presented. The AM were enriched from BAL cell samples harvested from healthy volunteers and stimulated with WTC. The concentrations of IL-26 in the cell-free conditioned media were measured using ELISA. Gene expression analyses on the cells were performed using RT-PCR. (A) IL-26 protein concentrations in cell-free conditioned media from AM (n=4). The rest of the graphs show gene expression for (B) IL-26, (C) IL-10R2, (D) IL-20R1, (E) NF-κB, (F) STAT1, and (G) STAT3 in AM. The P-values are according to the parametric paired t test whereby (A,B) are according to the one-tailed test and (C–G) according to the two-tailed test. The horizontal lines indicate means and the P-values <0.05 are considered significant.

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