Figure 3
(A) Reporting of blinding, randomization and sample size calculation in the MCAO literature collated from systematic reviews and summarized in 2007 in Sena et al. [8] (column 1), from the journal Stroke from 2010 to 2013 reported by Minnerup et al. [10] (column 2), and from 2014 to 2016 reported here (column 3). (B) Reporting of blinding, randomization and sample size calculation in the experimental lacunar stroke literature from the systematic review of 2012 [12] (column 1), and from 2012 to 2017 reported here (column 2).
Reporting of risks of bias in the recent literature compared with previous estimates.

(A) Reporting of blinding, randomization and sample size calculation in the MCAO literature collated from systematic reviews and summarized in 2007 in Sena et al. [8] (column 1), from the journal Stroke from 2010 to 2013 reported by Minnerup et al. [10] (column 2), and from 2014 to 2016 reported here (column 3). (B) Reporting of blinding, randomization and sample size calculation in the experimental lacunar stroke literature from the systematic review of 2012 [12] (column 1), and from 2012 to 2017 reported here (column 2).

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