Coinfection markedly increased circulating and tissue SAA levels
(A) Gene expression of SAA was measured in the lung by Taqman RT-qPCR. (B) SAA protein in the lung homogenate lysate, (C) BALF, and (D) serum was measured by ELISA. (E) RvD1 levels in the serum was measured by ELISA. (F) The relative ratio of SAA/RvD1 was determined for the matching serum samples. n=6–10, *P<0.05, one-way ANOVA compared with SAL or IAV as indicated.