(A) Grey-value distribution histograms of the samples obtained from WB, Bio-Oss control and a human mandibular healthy site. Peaks indicated with * are faked and due to mismatches of the samples in the field of view. (Top inset): 2D HT slice indicating few clusters of fully mineralized bone. (B) Three-dimensional images of Bio-Oss: (panel a) histological section with H&E staining, as a reference; (panels b–d) subvolume of the 3D HT reconstruction. To improve visualization, in each 3D image all phases were virtually deleted, except for: (b) bone and ECM, (c) bone and (d) ECM. Scale bar=250 μm. (C) Three-dimensional images of WB sample: (a) histological section with H&E staining; (panels b–d) subvolume of the 3D HT reconstruction. To improve visualization, in each 3D image all phases were virtually deleted, except for: (b) woven bone and vessels, (c) WB and (d) vessels. Red arrowheads indicate portions of vessels to distinguish them from possible artefacts. Scale bar=250 μm.