Figure 2.
![(A) Domain architecture of the PRC1 core proteins: the RING1 proteins and the PCGF proteins. (B) Structure of the RING1B RAWUL domain/CBX7 cbox domain (PDB: 3GS2, [27]). (C) Structure of the RING1B RAWUL domain/RYBP C-terminal domain (PDB: 3IXS, [27]). (D) Structure of the PCGF1 RAWUL domain/BCORL1 PFUD domain (PDB: 4HPL, [30]). (E) Structure of the RING1B ring domain–UBcH5c fusion/PCGF4/nucleosome complex (PDB: 4R8P, [11]). Single E2–E3 ligase shown for clarity.](https://port.silverchair-cdn.com/port/content_public/journal/biochemsoctrans/45/1/10.1042_bst20160173/2/bst-2016-0173c_02.jpeg?Expires=1717031428&Signature=WkSs7T5PjAzcdADtzLgxRlXKM3b8adttAiRXglABy~gtZ63M~YirPACUG7wa7tp4IoW65c0jklaJAXcVJl32DOtIywPjFJsEa7~2JR5Uyki2vAoeRR-63ab9SlLclFCH2~eHoPUnXNXW5Olt0ABhBaZlJ1gE0zjHKbwryB9gYb1UlzfQREhTzpgs9M49N~jVWTJ6McjbJSlmymJgwtScmTfTk1I1uD4e3dMn77fkruxI1~DjPz62Tq1HAefKQSu~FMqp8wXph7MjPM06jujDJZAyzeBq~qnVPnUf~xGPeLUEg8-Q3stiCSRaBwf4NG~YMVJojet-KgA5SQIRnfpHAQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The PRC1.
(A) Domain architecture of the PRC1 core proteins: the RING1 proteins and the PCGF proteins. (B) Structure of the RING1B RAWUL domain/CBX7 cbox domain (PDB: 3GS2, [27]). (C) Structure of the RING1B RAWUL domain/RYBP C-terminal domain (PDB: 3IXS, [27]). (D) Structure of the PCGF1 RAWUL domain/BCORL1 PFUD domain (PDB: 4HPL, [30]). (E) Structure of the RING1B ring domain–UBcH5c fusion/PCGF4/nucleosome complex (PDB: 4R8P, [11]). Single E2–E3 ligase shown for clarity.
