Figure 6
The top panel is CHIKV nsP2-Pro (PDB ID: 3TRK) and the lower panel is SINV nsP2-Pro (PDB ID: 4GUA). The alpha carbons of the two structures were aligned with an RMSD of 1.024 Å (1 Å=0.1 nm) for 250 atom pairs. The active site catalytic dyad (Cys-His) is circled in green. Molecular graphics and analyses were performed with the UCSF Chimera package. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco (supported by NIGMS P41-GM103311) [40].
Stereo view of the electrostatic surface colouring of CHIKV nsP2-Pro and SINV nsP2-Pro

The top panel is CHIKV nsP2-Pro (PDB ID: 3TRK) and the lower panel is SINV nsP2-Pro (PDB ID: 4GUA). The alpha carbons of the two structures were aligned with an RMSD of 1.024 Å (1 Å=0.1 nm) for 250 atom pairs. The active site catalytic dyad (Cys-His) is circled in green. Molecular graphics and analyses were performed with the UCSF Chimera package. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California, San Francisco (supported by NIGMS P41-GM103311) [40].

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