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Keywords: induced pluripotent stem cells
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Neuronal Signal (2022) 6 (1): NS20210054.
Published: 08 April 2022
... recapitulate all features of DS-AD. Cells differentiated from human-induced pluripotent stem cells (iPSCs), isolated from individuals with genetic diseases, can be used to model disease-related cellular and molecular pathologies, including DS. In this review, we will discuss the limitations of mouse models...
Neuronal Signal (2021) NS20210019.
Published: 13 December 2021
... with JISC. cell replacement embryonic stem cells foetal cells Huntington's disease induced pluripotent stem cells transplantation The underpinning concept of cell therapies in regenerative medicine is restoration of structure and function. This can be achieved through several approaches...
Neuronal Signal (2021) 5 (4): NS20210027.
Published: 09 November 2021
... provide an alternative accessible experimental platform which, when combined with NVU cell types differentiated from human induced pluripotent stem cells (iPSCs), can produce valuable models in which to study NVU structure and BBB (dys)function ( Figure 1 ). As iPSCs can be differentiated into all...