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Keywords: TLX
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Neuronal Signal (2019) 3 (2): NS20180208.
Published: 06 June 2019
... and their ubiquity in various states of health and disease have sometimes obscured the progress that has been made in unraveling their mechanisms and regulation. A recent study by Kozareva et al. ( Neuronal Signaling (2019) 3 ), provides evidence that the orphan nuclear receptor TLX is central to communication...
Neuronal Signal (2019) 3 (1): NS20180177.
Published: 22 February 2019
.... A disruption in this pathway has been associated with impaired neurogenesis yet the specific molecular mechanisms by which this interaction occurs remain unclear. The orphan nuclear receptor TLX (Nr2e1; homologue of the Drosophila tailless gene) is a key regulator of hippocampal neurogenesis, and we have shown...