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Keywords: TLX
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Articles
Paul J. Lucassen, Anne-Marie van Dam, Prasanna Kandel, Pascal Bielefeld, Aniko Korosi, Carlos P. Fitzsimons, Mirjana Maletic-Savatic
Journal:
Neuronal Signaling
Neuronal Signal (2019) 3 (2): NS20180208.
Published: 06 June 2019
... and their ubiquity in various states of health and disease have sometimes obscured the progress that has been made in unraveling their mechanisms and regulation. A recent study by Kozareva et al. ( Neuronal Signaling (2019) 3 ), provides evidence that the orphan nuclear receptor TLX is central to communication...
Articles
Danka A. Kozareva, Gerard M. Moloney, Alan E. Hoban, Valerio Rossini, Ken Nally, John F. Cryan, Yvonne M. Nolan
Journal:
Neuronal Signaling
Neuronal Signal (2019) 3 (1): NS20180177.
Published: 22 February 2019
.... A disruption in this pathway has been associated with impaired neurogenesis yet the specific molecular mechanisms by which this interaction occurs remain unclear. The orphan nuclear receptor TLX (Nr2e1; homologue of the Drosophila tailless gene) is a key regulator of hippocampal neurogenesis, and we have shown...