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Keywords: Alzheimers disease
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Neuronal Signal (2022) 6 (1): NS20210054.
Published: 08 April 2022
... of chromosome 21 (trisomy 21) and are more likely to develop early-onset Alzheimer’s disease (AD) than the general population. Changes in expression of human chromosome 21 (Hsa21)-encoded genes, such as amyloid precursor protein ( APP ), play an important role in the pathogenesis of AD in DS (DS-AD). However...
Neuronal Signal (2021) 5 (2): NS20200101.
Published: 14 June 2021
...Kelsey Hanson; Kate Fisher; Nigel M. Hooper Cognitive dysfunction is a key symptom of ageing and neurodegenerative disorders, such as Alzheimer’s disease (AD). Strategies to enhance cognition would impact the quality of life for a significant proportion of the ageing population. The α-klotho...
Neuronal Signal (2019) 3 (4): NS20190068.
Published: 28 November 2019
...Thaddeus K. Weigel; Joshua A. Kulas; Heather A. Ferris Type 2 diabetes is associated with adverse central nervous system effects, including a doubled risk for Alzheimer’s disease (AD) and increased risk of cognitive impairment, but the mechanisms connecting diabetes to cognitive decline...