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Keywords: vascular smooth muscle
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Essays Biochem (2020) 64 (3): 423–441.
Published: 18 August 2020
... and on vascular smooth muscle cells. TXA 2 is mainly produced by platelets (via COX-1) and its production is increased when platelets are activated. It promotes smooth muscle contraction, acting as a vasoconstrictor, and is a potent activator of platelets causing their aggregation leading to thrombus formation...