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Keywords: transgenerational epigenetic inheritance
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Essays Biochem (2019) 63 (6): 649–661.
Published: 22 November 2019
... comparable developmental windows. The evolutionary mechanisms which drove this divergence are unknown, nevertheless a direct consequence of retaining epigenetic memory in the form of 5mC is the enhanced potential for transgenerational epigenetic inheritance (TEI). Given that DNA methylation dynamics remains...
Essays Biochem (2016) 60 (2): 191–202.
Published: 15 October 2016
... has reverted. Such transgenerational epigenetic inheritance requires that information be stored in the germline in response to exogenous stressors. One of the most elusive questions in the field of epigenetic inheritance is the identity of such inherited factor(s). Answering this question would allow...