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Keywords: synthetic biology
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Articles
Essays Biochem (2021) 65 (2): 309–318.
Published: 26 July 2021
... base for a microbial cell factory excelling in synthetic biology applications where evolution meets rational engineering. Correspondence: Suvi Santala ( suvi.santala@tuni.fi ) 26 01 2021 23 02 2021 25 02 2021 © 2021 The Author(s). Published by Portland Press Limited...
Articles
Essays Biochem (2021) 65 (2): 381–392.
Published: 26 July 2021
... engineering industrial biotechnology metabolic engineering physiology synthetic biology Vibrio natriegens Currently, most biotechnological production processes are carbohydrate-based (e.g. glucose or sucrose) [ 1 ] applying industrially established microbial systems such as Escherichia coli...
Articles
Essays Biochem (2021) 65 (2): 393–403.
Published: 26 July 2021
...Jian-Wen Ye; Guo-Qiang Chen With the rapid development of systems and synthetic biology, the non-model bacteria, Halomonas spp., have been developed recently to become a cost-competitive platform for producing a variety of products including polyesters, chemicals and proteins owing...
Includes: Supplementary data
Articles
Essays Biochem (2021) 65 (2): 247–260.
Published: 26 July 2021
... and synthetic biology have broadened the horizon of heterologous protein production using multiple expression platforms. Selection of a suitable expression system depends on a variety of factors ranging from the physicochemical properties of the target protein to economic considerations. For more than 40 years...
Articles
Essays Biochem (2021) 65 (2): 143–145.
Published: 26 July 2021
...Pablo I. Nikel; Diethard Mattanovich An increasingly large number of microbial species with potential for synthetic biology and metabolic engineering has been introduced over the last few years, adding huge variety to the opportunities of biotechnology. Historically, however, only a handful...
Articles
Essays Biochem (2021) 65 (2): 293–307.
Published: 26 July 2021
... recently, P. pastoris was also employed for the production of metabolites by metabolic engineering. A well-annotated genome sequence [ 2 ] as well as genome-editing tools and collections of synthetic biology parts and devices make P. pastoris a promising chassis for synthetic biology applications [ 3...
Articles
Essays Biochem (2021) 65 (2): 173–185.
Published: 26 July 2021
... production are summarized. Further, the recent progress in employing metabolic engineering and synthetic biology strategies in B. subtilis platform strain to produce commodity chemicals is systematically introduced and compared. Finally, the major limitations for the further development of B. subtilis...
Articles
Essays Biochem (2021) 65 (2): 197–212.
Published: 26 July 2021
... (CC BY) . Corynebacterium glutamicum extremolytes metabolic engineering plant phenols synthetic biology terpenoids Corynebacterium glutamicum is a Gram-positive, non-spore-forming facultative anaerobic bacterium with a moderate to high GC content belonging to the phylum...
Articles
Essays Biochem (2019) 63 (6): 813–825.
Published: 14 November 2019
... 2019 23 10 2019 24 10 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 CRISPR epigenetics epigenome editing epigenomics methyltransferases synthetic biology The complex repertoire of covalent modifications of DNA...
Articles
Essays Biochem (2016) 60 (4): 347–355.
Published: 30 November 2016
...Vitor B. Pinheiro; Phil Macnaghten; Richard Owen; Roland Jackson In this article we provide a short review of the debate on responsible innovation and its intersection with synthetic biology, focusing on initiatives we have witnessed and been involved with in the UK. First, we describe the ways...
Articles
Essays Biochem (2016) 60 (4): 337–346.
Published: 30 November 2016
... desirable functions for bioindustry, such as improved genome stability, increased transformation efficacy and improved production of biomaterials. The minimal genome as a chassis genome for synthetic biology can be used to construct custom-designed genomes for various practical and industrial applications...
Articles
Essays Biochem (2016) 60 (4): 381–391.
Published: 30 November 2016
... biological circuits synthetic biology Artificial intelligence (AI) can be defined as the decision-making capabilities of machines [ 1 ]. Machines are most commonly regarded as designed, multi-part objects that perform predetermined mechanical tasks. To date all commercial machines are constructed...
Articles
Essays Biochem (2016) 60 (4): 325–336.
Published: 30 November 2016
.... Synthetic biology aims to make the engineering of biology easier, offering an opportunity to control natural systems and develop new synthetic systems with useful prescribed behaviours. However, in many cases, it is not understood how individual cells should be programmed to ensure the emergence...