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Keywords: sphingolipids
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Essays Biochem (2022) 66 (4): 333–344.
Published: 16 September 2022
... and differences in lipid homeostasis in stem-like versus more mature AML subtypes as well as from normal HSCs are emerging. Here, we discuss the latest findings from studies of lipid function in LSCs, with a focus on sphingolipids (SLs) as stemness/lineage fate mediators in AML, and the balance of fatty acid...
Essays Biochem (2021) 65 (5): 813–845.
Published: 02 November 2021
... function of the cell. This review summarises the biosynthesis of the lipids of the mammalian cell; phospholipids, sphingolipids and cholesterol and how lipid diversity is achieved. The fatty acids (FAs) are the main building blocks of lipids and contribute to the diversity. Lipid synthesis is intimately...
Essays Biochem (2020) 64 (3): 579–589.
Published: 24 June 2020
...Ana Gomez-Larrauri; Natalia Presa; Asier Dominguez-Herrera; Alberto Ouro; Miguel Trueba; Antonio Gomez-Muñoz Sphingolipids are a class of complex lipids containing a backbone of sphingoid bases, namely the organic aliphatic amino alcohol sphingosine (Sph), that are essential constituents...