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Keywords: protein structure
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Articles
Essays Biochem (2023) 67 (3): 493–503.
Published: 18 April 2023
... in forming the LCC. Here, we summarize the current literature on GEs, with a focus on their activities, modularity and structure. carbohydrate esterase enzymology lignin-carbohydrate complex lignocellulose protein structure © 2023 The Author(s). 2023 This is an open access article...
Articles
Essays Biochem (2023) 67 (2): 243–253.
Published: 29 March 2023
... protein aggregation protein structure Proteins rely on a high degree of conformational flexibility to fold into their native states and facilitate the extensive interactions with a wide variety of binding partners that underlie biological function. Reaching and maintaining such native structures...
Articles
Essays Biochem (2023) 67 (2): 165–174.
Published: 29 March 2023
... mass spectrometry protein structure Hydrogen–deuterium exchange (HDX) is a labelling technique that monitors the exchange of hydrogen for deuterium when a molecule of interest is placed in deuterated solvent (usually D 2 O). When a 1H (protium, referred to as ‘H’) is exchanged for a 2H...
Articles
Essays Biochem (2020) 64 (5): 819–830.
Published: 23 October 2020
... and repair protein structure synthetic lethality The RecQ family of helicases unwind DNA in a 3′ to 5′ direction and contribute to the maintenance of genome integrity by playing important roles in multiple DNA repair pathways. Single-celled organisms and lower eukaryotes generally contain a single...
Articles
Essays Biochem (2020) 64 (4): 649–680.
Published: 25 September 2020
... structure and the underlying chemistry and physics that is used to uncover protein structure. We start with the chemistry of amino acids and how they interact within, and between proteins, we also explore the four levels of protein structure and how proteins fold into discrete domains. We consider...
Articles
Essays Biochem (2020) 64 (5): 807–817.
Published: 29 July 2020
... with Portland Press and the Biochemical Society under a transformative agreement with CAUL. biochemistry DNA synthesis and repair enzyme activity Fanconi anemia protein structure ubiquitin ligases Fanconi anemia (FA) is a genetic disorder that has intrigued scientists and illuminated medical...