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Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 885–904.
Published: 22 December 2021
... to the increased severity of the disease during the progression when neuroinflammation plays a critical role. The activation of immune cells, especially microglia, plays a crucial role in the development of neurodegenerative diseases. Molecular sensors within these microglia, such as the NLRP3 inflammasome...