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Keywords: metabolic coupling
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Essays Biochem (2023) 67 (1): 17–26.
Published: 03 March 2023
... astrocyte-neuron metabolic coupling by promoting PFKFB3 destabilization and attenuation of glycolysis in neurons, facilitating PPP activity for antioxidant protection. In astrocytes, APC/C-Cdh1 activity is very low resulting in PFKFB3 stabilization and higher basal glycolytic rate and lactate release...