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Keywords: liquid-liquid phase separation
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Articles
Journal:
Essays in Biochemistry
Essays Biochem (2022) 66 (7): 1013–1021.
Published: 16 December 2022
...–liquid phase separation in vitro and forms or associates with membrane-less organelles in cells. Biomolecular condensation driven by phase separation can influence the biological activities of tau including its ability to polymerize tubulin into microtubules. In addition, the high concentrations that tau...
Articles
Alexander V. Fonin, Iuliia A. Antifeeva, Irina M. Kuznetsova, Konstantin K. Turoverov, Boris Y. Zaslavsky, Prakash Kulkarni, Vladimir N. Uversky
Journal:
Essays in Biochemistry
Essays Biochem (2022) 66 (7): 831–847.
Published: 16 December 2022
... are compartmentalized into the liquid-like biomolecular condensates, which are formed via liquid–liquid phase separation (LLPS) and are not surrounded by the membrane, are revolutionizing the modern biology. These phenomena are interlinked, as the presence of intrinsic disorder represents an important requirement...
Articles
Journal:
Essays in Biochemistry
Essays Biochem (2022) 66 (7): 821–830.
Published: 16 December 2022
...Samrat Mukhopadhyay; Susana Barrera-Vilarmau; João M.C. Teixeira; Monika Fuxreiter How do proteins interact in the cellular environment? Which interactions stabilize liquid–liquid phase separated condensates? Are the concepts, which have been developed for specific protein complexes also applicable...