... conformational dynamics hydrogen-deuterium exchange mass spectrometry intrinsically disordered proteins mass spectrometry protein structure Hydrogen–deuterium exchange (HDX) is a labelling technique that monitors the exchange of hydrogen for deuterium when a molecule of interest is placed...

... into native-like lipid environments that more accurately represent the biological membrane. Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) has emerged as a versatile tool for probing protein dynamics in solution. The continued development of HDX-MS methodology has allowed practitioners to investigate...