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Keywords: deubiquitinase
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Essays Biochem (2022) 66 (2): 147–154.
Published: 05 August 2022
... is a widespread, essential PTM that regulates most, if not all cellular processes. Ubiquitin is added to target proteins via a well-defined enzymatic cascade involving a range of conjugating enzymes and ligases, while its removal is catalysed by a class of enzymes known as deubiquitinases (DUBs). Many human...