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Keywords: cell migration
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Essays Biochem (2020) 64 (3): 579–589.
Published: 24 June 2020
... of eukaryotic cells. They were first described as major components of cell membrane architecture, but it is now well established that some sphingolipids are bioactive and can regulate key biological functions. These include cell growth and survival, cell differentiation, angiogenesis, autophagy, cell migration...
Essays Biochem (2019) 63 (5): 631–637.
Published: 11 October 2019
...George Butler; Jonathan Rudge; Philip R. Dash The complexity of biological systems creates challenges for fully understanding their behaviour. This is particularly true for cell migration which requires the co-ordinated activity of hundreds of individual components within cells. Mathematical...
Essays Biochem (2019) 63 (5): 521–533.
Published: 11 October 2019
... and biochemical properties conferred by the different keratin isotypes and their modifications serve as finely tunable modulators of epithelial cell migration. We will furthermore argue that KFs together with their associated desmosomal cell–cell junctions and hemidesmosomal cell–extracellular matrix (ECM...
Includes: Supplementary data
Essays Biochem (2019) 63 (5): 535–551.
Published: 23 August 2019
... receptors, such as integrins, and form specialized adhesion complexes that mediate responses to different extracellular cues. In this review, we discuss the role of integrin adhesion complexes (IACs) in cell migration, highlighting the layers of regulation that are involved, including intracellular...
Essays Biochem (2019) 63 (5): 509–520.
Published: 29 July 2019
...Clare Garcin; Anne Straube Directed cell migration is critical for embryogenesis and organ development, wound healing and the immune response. Microtubules are dynamic polymers that control directional migration through a number of coordinated processes: microtubules are the tracks for long...
Essays Biochem (2019) 63 (5): 469–482.
Published: 26 July 2019
... endocytic proteins in cancer cell migration, focusing on clathrin, caveolin, flotillins and GRAF1. In addition, we highlight the relevance of the macropinocytic pathway in amoeboid-like cell migration. Correspondence: Elena Rainero ( e.rainero@sheffield.ac.uk ) 24 05 2019 27 06 2019 11...
Essays Biochem (2019) 63 (5): 595–606.
Published: 19 July 2019
...Shane P. Herbert; Guilherme Costa Cell migration is a fundamental biological process involved in tissue formation and homeostasis. The correct polarization of motile cells is critical to ensure directed movement, and is orchestrated by many intrinsic and extrinsic factors. Of these, the subcellular...