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Journal: Essays in Biochemistry
Essays Biochem (2021) 65 (7): 999–1011.
Published: 22 December 2021
... and excessive apoptosis which mirrors the final common pathway for neuronal death in ALS, PD and AD. Sphingomyelinase (SMase) and phospholipase (PL) enzymes process components of MLRs and therefore play central roles in MLR homeostasis and in neurotrophic signalling. We review the literature linking SMase...