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Keywords: amphisome
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Essays Biochem (2017) 61 (6): 637–647.
Published: 12 December 2017
... is the proinflammatory cytokine interleukin (IL)-1β, first reported in 1990 as being secreted from mammalian cells despite the absence of a leader peptide [ 3 , 4 ]. In this review, we summarize evidence for autophagy as a mechanism for unconventional secretion of such leaderless cargo. autophagy amphisome...