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Keywords: Parkinson's disease
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Essays Biochem (2021) 65 (7): 885–904.
Published: 22 December 2021
... Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS). The prominent NLRP3 inflammasome triggers include amyloid β and tau oligomers in AD, α-synuclein in PD, and superoxide dismutase (SOD1) and TAR DNA-binding protein 43 (TDP43) in ALS. NLRP3 inhibitor treatment has...
Essays Biochem (2021) 65 (6): 913–925.
Published: 26 November 2021
... in Alzheimer’s disease (AD) and Parkinson’s disease (PD). In addition, controversies related to ER expression in the brain will be discussed. Understanding the spatiotemporal signaling of sex hormones in the brain can lead to more personalized prevention strategies or therapies combating neurodegenerative...
Essays Biochem (2016) 60 (2): 173–180.
Published: 15 October 2016
... of the Biochemical Society and distributed under the Creative Commons Attribution Licence 4.0 (CC BY) . amyloid autophagy chaperone-mediated autophagy immunoglobulin light chain lysosome macroautophagy mTOR Parkinson's disease protein aggregation protein misfolding proteostasis rapamycin TFEB α...
Essays Biochem (2014) 56: 125–135.
Published: 18 August 2014
...Sarah Perrett; Shun Yu; Piu Chan α-Syn (α-synuclein) is a small soluble acidic protein that is extensively expressed in the nervous system. Genetic, clinical and experimental studies demonstrate that α-syn is strongly implicated in the pathogenesis of PD (Parkinson's disease). However...
Essays Biochem (2013) 55: 93–104.
Published: 27 September 2013
... advancements in the study of mitophagy mechanisms and regulation. 1 email tom.macvicar@bristol.ac.uk © The Authors Journal compilation © 2013 Biochemical Society 2013 Atg32 erythropoiesis mitochondrial dynamics mitochondrial dysfunction Nix parkin Parkinson's disease PINK1...