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Journal: Essays in Biochemistry
Essays Biochem (2019) 63 (6): 639–648.
Published: 22 November 2019
... and highlight the respective strengths and weaknesses of PacBio and Nanopore sequencing for this application. Although analysing epigenetic data from long-read platforms remains challenging, the ability to detect various modified bases from a universal sample preparation, in addition to the mapping and phasing...